Rhizoma smilacis Glabrae (tu fu ling)

Promotes Normal Urination*

Lin zheng (dysuria syndrome): tu fu ling dispels heat from lower jiao to treat re lin (heat dysuria) with burning sensations and painful urination.*

Chemical Composition: Saponin, rutin, resin, octacosanal, 16-hentriacontanone.*

Pharmacological Effects

Antineoplastic: Administration of tu fu ling has shown promising effects in the treatment of cancer. In animal studies, it is especially effective against cancers of the urinary bladder and liver.*

Effects on the urinary system

Tu fu ling could increase the excretion of uric acid, and had anti-gout effect. It could also treat albuminuria and restore renal functions.*

Acute and chronic nephritis

Tu fu ling 90g, water decoction being taken in three times. It had good edema-treating effect (Wen et al, 1998).*

Rhizoma Imperatae (bai mao gen)

Clears Heat and Promotes Urination*

Dysuria: bai mao gen treats re lin (heat dysuria), edema, and damp-heat jaundice by draining heat through urination.*

Hematuria due to Urinary Bladder heat: use Bai Mao Gen individually.*

Hematuria with deficiency heat: combine it with Ren Shen (Radix Ginseng), Sheng Di Huang (Radix Rehmanniae) and Fu Ling (Poria).*

Chemical Composition: Arundoin, cylindrin, ferneol, simiarenol, coixol.*

Pharmacological Effects

Diuretic: Decoction of Bai Mao Gen has demonstrated a diuretic effect in rabbits, with maximum effectiveness evident 5 to 10 days after the initiation of treatment.

Nephritis: Children with acute nephritis were treated with 32 to 59 doses of an herbal decoction, with marked reduction in edema, lowered blood pressure, absence of protein and blood cells in the urine, and normalization of urine. Out of 11 patients, there was complete recovery in 9 patients and moderate improvement in 2 patients.*

Diuretic effect

Water immersion fluid and decoction of bai mao gen had diuretic effect on rabbits.*

Antibacterial effect

Decoction of bai mao gen had significant inhibitory effect on Shigella flexneri and Shigella sonnei (Wen et al, 1998).*

Herba Taraxaci (pu gong ying)

Promotes Urination

Re lin (heat dysuria): Heat invading the Urinary Bladder manifests in burning pain on urination. In this case, the urine is usually scanty and yellow.*

Chemical Composition: Taraxasterol, Taraxerol

Pharmacological Effects

Markedly inhibits Staphylococcus aureus, Streptococcus haemolyticus, Neisseria catarrhalis, Diplococcus pneumoniae, Proteus vulgaris and Corynebacterium diphtheriae.*

Markedly increased human peripheral lymphoblast transformation rate, indicating activation of immunological function.*

Main Medical Effect of the Extracts from Herba taraxaci and Total Flavones in Chamaejasmine

Su Sheng-hua, JIN Ya-ping, QIN Xin-xi, SONG Yu-min. Xi Bei Nong Ye Xue Bao. 2008; 17(4): 181-185.

In order to study the bacteriostasis and anti-inflammatory and antipyretic effects of the extracts from Herba taraxaci and total flavones in chamaejasmine. The bacteriostasis and the minimal inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of three extracts on S. aureas, E. coli, S. dysagalactie were detected by plate process and test tube method. The antipyretic and anti-inflammatory action were observed by pyretic rabbits induced by intravenous injection of milk and mice with ear swelling induced by xylene. The results showed that the fraction of Herba taraxaci eluted with 40% of ethanol (40%HT) and total flavones in chamaejasmine (TFC) had midrange inhibitory effect on those bacteria, and the combination of 40% HT and TFC had significant efficacy. TFC and 40% HT at dose of 500, 250 mg/kg and 90% HT at 500 mg/kg had significant inhibitory effect on ear swelling in mice(P<0.01>. Two extracts from Herba taraxaci both had significant antipyretic action(P<0.01 orP<0.05>, but TFC didn’t have the function.*

Bai xian pi (Cortex Dictamni)

Chemical Composition: Alkaloids, dictamnine and skimmianine, triterpenoids; dictamnolactone and obacunone, dictamnolide, campesterol, sitosterol and limonoids*

Pharmacological Effects

Antifungal: The water decoction of Bai Xian Pi has an inhibitory effect against various pathogenic fungi.*

Treats anorectal conditions*

The alkaloids and limonoids from Cortex Dictamni are anti-bacterial, anti-fungal*

Treats Chlamydia*

The affect of dictamnus dasycarpus on ha and 5-ht in acute inflammation

Hanghui, HUANG Leshan, HE Zhiguang. Xian Dai Yi Yuan. 2008; 8(10): 31-33.

Objective To research the effect of Dictarnnus Dasycarpus on anti-inflammation to provide experimental basis for its clinical application. Methods To study the histamine and 5-HT in the swollen rat toes caused by egg white. Results Dictamnus Dasycarpus could inhibit histamine and 5-HT in various of kinds of inflammation model..*

Chuan mu tong (Caulis Clematidis Armandii)

Promotes Urination

Lin zheng (dysuria syndrome): chuan mu tong (Caulis Clematidis Armandii) is commonly used to treat dysuria characterized by burning sensations and pain during urination, indicating an accumulation of damp-heat in the urinary bladder.*

Chemical Composition: Climontanoside B, five triterpenoid saponins

Pharmacological Effects

Diuretic: Oral ingestion or intravenous injection of a decoction of Chuan Mu Tong creates marked diuretic results in rabbits.*

Cardiotonic and diuretic effect*

mu tong decoction and alcohol infusion had obvious diuretic effect.*

Urinary tract infections*

Dao Chi San combining che qian zi, bian xu, fu ling, mu tong, huang qin, gan cao (Wen et al, 1998).*

Comparative study on the Efficacy and Toxicity between Clematis armandii Franch and C. Montana Buch., -Hum Aqueous Extract

Zhang Baijia, Cao Yu, Liu Liu, Pan Jia. Si Chuan Zhong Yi. 2008; 26(2): 38-39.

Objective: To compare the anti-inflammatory and diuretic effects of Clematis armandii Franch (I) and C. Montana Buch. -Hum (II), the acute toxicity also be studied. Methods: Anti-inflammatory effect was observed on carrageenan and egg-whlte induced ankle joint swelling mouse model respectively, diuretic effect was observed on mouse model by testing the urine volume and the contents of K +, Na + in the urine. The acute toxicity was tested by general method. Results: I and II had significant anti-inflammatory effects. The urine volume and the contents of K +, Na + in the urine were obviously increased by II, and only the urine volume and the contents of K + were increased by I . The maximum tolerated dose of I or II was 300g crude drug/kg via i.g. Conclusion: II has better anti-inflammatory and diuretic effects than I, and I and II have no significant acute toxicity on mice.*

References

Chang Yong Zhong Yao Xian Dai Yan Jiu Yu Lin (Recent Study & Clinical Application of Common Traditional Chinese Medicine), 1995; 267: 269

Guang Dong Yi Xue (Guangdong Medicine), 1965; 3:28

Huo X, Weng X, Li Y. Clinical observation on perinatal Chlamydia trachomata infection. Zhonghua Fu Chan Ke Za Zhi. 1995 Aug;30(8):460-2.

Int. J. Crude Drugs Res, 1990; 28(1): 39

Ji Lin Zhong Yi Yao (Jilin Chinese Medicine and Herbology), 1991; (2): 12

Liao Ning Zhong Yi Za Zhi (Liaoning Journal of Chinese Medicine), 1977; (1); 18

Wen Weiliang, Fang Shuting, Li Chunsheng, Gao Xiaoshan, Hu Shilin, Chen Fuxin, Zhao Ronglai, Wang Junxuan, Shi Zaixiang, Su Chenlian, Lin Lan, Ye Yisen, Hu Jin, Yu Yingqi, Yu Zhenxuan, Yao Baosen, Wu Jin, Zhang Shuliang, Hou Rongxian, Kou Qiu’ai. Clinical Chinese materia medica, Henan Science & Technology Press, 1998

Zhong Cao Yao (Study of Chinese Herbal Medicine), 1976: 527

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.