Resist

$22.00
PAN88

Resist is formulated with as many as seventeen powerful immune boosting and modulating herbal extracts. Resist strengthens the innate immune system by increasing NK cells, macrophages phagocytes and leucocytes (WBC) in the spleen and thymus.*

Supplement Facts

Serving Size:1 capsules

Servings Per Container: 60

Amount Per Serving

% Daily Value

Huang Qi - Astragalus membranaceus 75mg
Ling Zhi - Ganoderma lucidum 50mg
Dang Shen - Codonopsis pilosula 50mg
Bai Zhu - Atractylodes macrocephala 30mg
Gan Cao - Glycyrrhiza uralensis 10mg
Shu Di Huang - Rehmannia glutinosa 29mg
Sha Shen - Adenophora stricta 29mg
Wu Wei Zi - Schisandra chinensis 23mg
Sheng Jiang - Zingiber officinale 21mg
Da Zao - Ziziphus jujuba 10mg
Ji Xue Teng - Spatholobus suberectus 29mg
Tu Si Zi - Cuscuta hygrophilae 29mg
Shan Yao - Dioscorea polystachya 29mg
Jie Gen - Platycodon grandiflorus 23mg
Nu Zhen Zi-Ligustrum lucidum 29mg
Bai Shao - Paeonia lactiflora 15mg
Chen Pi - Citrus reticulata 15mg
† Daily Value not established.

Resist

60 x 500 mg Capsules

Panaxea’s Gold Label Resist was formulated by Dr. Daniel Weber PhD MSC in 1991 and has been most successful since its inception nearly 26 years ago. Resist is formulated with as many as seventeen powerful immune boosting and modulating herbal extracts, supporting immune function in liver, lung, kidney, spleen, thymus, and all organs of the gastrointestinal tract. Resist strengthens the innate immune system by increasing NK cells, macrophages phagocytes and leucocytes (WBC) in the spleen and thymus.*

Resist is strongly recommended as part of a cancer support protocol or chemoprevention.*

Actions 

Improves respiratory function*

Enhances Innate and Adaptive immune function*

Prevents viral reproduction*

Expedites recovery from viral and bacterial infections*

Enhances gastrointestinal immune response*

Increases WBC production*

Inhibits tumour growth*

Suggested Use: 

2-3 capsules a daily.

Cautions and Contraindications: 

Do not use during acute stage of flu or cold. Because these herbs have potent immune enhancing effects, they should not be prescribed for patients taking immunosuppressant following organ transplant surgery. Despite their weak constitution, use of some immune enhancing herbs can increase the risk of rejection and severely compromise the patient's health. 

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Review by Dr. Daniel Weber

A quick review of some of the critical immune-enhancing Chinese herbs.*

In the history of traditional Chinese medicine (TCM), the documentary records for the Chinese word "immune" was first seen in the 18th century in the book Mian Yi Lei Fang (Formulas for the Immunity from Plague). TCM already knew about the theory and practice of immunology and infectious diseases from earlier dynasties. In chapter 72 of the Suwen (The Book of Plain Questions), when the Yellow Emperor asked about the seasonal epidemic diseases, his chief advisor Qi Bo answered that in order to defend against those diseases, one should always keep his healthy energy abundant, and the evils will not invade. The dialogue clearly shows that TCM regards "healthy energy" as the general defence mechanism against infectious diseases.*

Astragalus

Many Chinese herbs have strong immunity-enhancing effects. Astragalus is very well-known for its powerful “non-specific" immune system stimulating capacity, which works by increasing the numbers and activity of roving white blood cells.*

A study conducted at the University of Texas Medical Centre in Houston showed that astragalus extracts were able to completely restore the function of immune cells in cancer patients. Research has confirmed repeatedly that astragalus increases both specific and non-specific immunity (Chu et al, 1988, Sun et al 1, 1983 & Sun et al 2, 1983). In a clinical trial of 115 leucopenia patients, astragalus was found to be associated with an "obvious rise of the white blood cell (WBC) count" with a dose-dependent relationship (Weng, 1995). In addition, astragalus works well with concurrent drug therapy in enhancing the overall effectiveness of the treatment. It also potentiates the anti-tumour effect of chemotherapy drugs (Chu et al 1 , 1988) while reversing drug-induced immune suppression (Chu et al 2, 1988). Lastly, astragalus demonstrates anti-cancer activity by increasing the content of camp and inhibiting the growth of tumour cells (Yeung, 1996).*

Astragalus enhances immune function by increasing the activity of certain white blood cells, which increases the production of antibodies (IgA and IgG) and increases the production of interferon. It stimulates natural killer cells (Zand, 1999, Leung & Foster, 1996).*

In addition to boosting immunity, Astragalus has antibacterial, adaptogenic, anti-inflammatory, and anti-viral effects. It contains numerous components, including polysaccharides, flavonoids, triterpene glycosides, amino acids, and trace minerals (Shu, 1986). It owes most of its immune enhancing effects to polysaccharides; a group of complex sugars responsible for initiating the immune response. Polysaccharides work with other key components to strengthen and build the immune system.*

According to James Duke, Ph.D., the world's leading authority on healing herbs, Astragalus increases white blood cell production of the body's own anti-viral compounds alpha-and gamma-interferon, which generally protect against viral invasion (Duke, 1997).*

Astragalus also enhances T-cell production and stimulates macrophages (Yoshida et al, 1997).*

In one study 8 grams of Astragalus given orally to 14 healthy volunteers for 2 months significantly increased interferon-inducing ability of blood cells. In another study Astragalus extract given to healthy adults for 20 days increased blood IgM, IgE and cAMP [and A herbal tincture of Astragalus stimulated CD4 and CD8 T-cells and induced the production of CD69 in human subjects ) Brush et al, 2006).*

Astragalus flavonoids are reported to increase in vivo cell-mediated immunity in guinea pigs and mice (Zhuang, 1992 & Yuan et al, 1990). Astragalus appears to enhance cell-mediated immunity by increasing the number of T-helper cell type 2 cytokines, increasing levels of tumour necrosis factor and interleukin-6 (Zhuang, 1992).*

Ganoderma

Ganoderma (ling zhi) has been traditionally used to tonify blood and vital energy. It is thus essential in rebuilding a patient's constitution. Ganoderma increases the number of white blood cells and inhibits the growth of various viruses and bacteria associated with the flu. It has been demonstrated to enhance the immune system in various clinical studies. The specific effects of ganoderma include an increase in monocytes, macrophages and T-lymphocytes (Wang et al, 1997,  Van der Hem et al, 1995, Haak-Frendscho et al, 1993 & Tanaka et al, 1989). There is also an increased production of cytokine, interleukin, tumour necrosis factor and interferon. Furthermore, ganoderma has a broad spectrum of antibacterial activities, inhibiting the growth of pneumococci, streptocci (type A), staphylococci, e. coli, b. dysentarie and pseudomonas, among others (Yeung, 1996). The proliferative functions and counts of T and B lymphocytes as well as and killing activity of NK cells were higher than those in tumour control group in Ganoderma lucidum spore powder on immune function of mice with Lewis lung cancer (Yang Wei et al, 2012).*

Radix Codonopsis

Radix Codonopsis attenuates the depression of immune function and different molecular weights of Codonopsis polysaccharides are not statistically significant in genetic material injury (Yu  & Wang, 2016). Also the influence Radix Codonopsis on NK cell activity and the ability of lymphocyte proliferation, IL-4 and IL-2 level in serum were significantly enhanced (Schen et al, 2015).*

Schisandrae chinensis

Research result showed that fructus schisandrae polysaccharide plays a tumour suppressor role through improving cellular immune and organ immune function, which presents a typical dose dependent manner and enhances with dosage increasing (Gan, 2013).*

Spatholobus suberectus

Hela cells were obviously inhibited by the serum containing Spatholobus suberectus and it had the inhibitory effects on Hela cells (Liang et al, 2011).*

Cuscuta chinensis

Cuscuta seed could promote the growth of the immune organs such as spleen and thymus gland (P<0.05) and improve the phagocytosis function of macrophagocyte (P<0.05); also it could stimulate the cell multiplication of splenic lymphocyte and induce the production of interleukins (Zhang & Shi, 2006).*

Fructus Ligustri Lucidi

Polysaccharides from Fructus Ligustri Lucidi increase the immunity of tumour-bearing mice (Li et al, 2008).*

 References

Block KI & Mead MN. Immune System Effects of Echinacea, Ginseng, and Astragalus: A Review. Integrative cancer therapies. 2(3); 2003pp. 247-267 doi 10.1177/1534735403256419

Brush J, et al. The effect of Echinacea purpurea, Astragalus membranaceus and Glycyrrhiza glabra on CD69 expression and immune cell activation in humans. Phytotherapy Research. Volume 20, Issue 8, pages 687–695, August 2006

Chen Jia-yu, et al. Effect of wen codonopsis pilosula and baitiao codonopsis pilosula-polysaccharide on the S180 tumour and the blood cytokines in mice. Zhong Hua Zhong Liu Fang Zhi Za Zhi. 2015, (17):1357-1362

Chu DT, et al.  2 Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionated astragalus membranaceus in vivo. Journal of Clinical & Laboratory Immunology Mar 1988;25(3):125-9.

Chu DT, et al. 1 Fractionated extract of astragalus membranaceus, a Chinese medicinal herb, potentiates LAK cell cytotoxicity generated by a low dose of recombinant interleukin-2. Journal of Clinical & Laboratory Immunology Aug 1988;26(4):183-7.

Chu DT, et al. Immunotherapy with Chinese medicinal herbs. I. Immune restoration of local xenogenetic graft-versus-host reaction in cancer patients by fractionated astragalus membranaceus in vitro. Journal of Clinical & Laboratory Immunology Mar 1988;25(3):119-23.

Duke, James A., Ph.D. The Green Pharmacy. Emmaus, PA: Rodale Press, 1997, p. 544.

Gan Lu. Regulating effect of fructus schisandrae polysaccharide on tumour growth and immune function of H_ (22) vaccination mice. Mian Yi Xue Za Zhi. 2013, (10): 867-870

Haak-Frendscho M, et al. Ling zhi-8: a novel T-cell mitogen induces cytokine production and up-regulation of ICAM-1 expression. Cellular Immunology Aug 1993;150(1):101-13.

Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, 2d ed. New York: John Wiley & Sons, 1996, 50-3.

Li L et al. Effect of Polysaccharides from Fructus Ligustri Lucidi on Immunity of Tumor-bearing Mice. Nan Jing Zhong Yi Yao Da Xue Xue Bao. 2008, (6): 388-390

Liang N, et al. Effects of serum containing Suberect spatholobus on Hela cells. Hua Xi Yao Xue Za Zhi. 2011, (1): 44-45

Liu Q-y, Yao Y-m, Yu Y, Dong N, Sheng Z-y (2011) Astragalus Polysaccharides Attenuate Postburn Sepsis via Inhibiting Negative Immunoregulation of CD4+CD25high T Cells. PLoS ONE 6(6): e19811. doi:10.1371/journal.pone.0019811 

Schulz V, Hansel R, Tyler VE. Agents that increase resistance to diseases. In: Rational Phytotherapy. New York :Springer–Verlag; 1998:269-285\

Shu HY. Oriental Materia Medica: A Concise Guide. Palos Verdes, CA: Oriental Healing Arts Press, 1986, 521-3. 

Sun Y, et al. 1 Immune restoration and/or augmentation of local graft versus host reaction by traditional Chinese medicinal herbs. Cancer July 1, 1983;52(1):70-3.

Sun Y, et al. 2 Preliminary observations on the effects of the Chinese medicinal herbs astragalus membranaceus and ganoderma lucidum on lymphocyte blastogenic responses. Journal of Biological Response Modifiers 1983;2(3):227-37.

Tanaka S, et al. Complete amino acid sequence of a novel immunomodulatory protein, ling zhi-9. An immuno-modulator from a fungus, ganoderma lucidum, having similar effect to immunoglobulin variable regions. Journal of Biological Chemistry Oct 5, 1989;264(28):16372-7.

Van der Hem LG, et al. Ling zhi-8: studies of a new immunomodulating agent. Transplantation Sep 15, 1995;60(5):438-43.

Wang SY, et al. The anti-tumour effect of ganoderma lucidum is mediated by cytokines released from activated macrophages and T-lymphocytes. International Journal of Cancer Mar 17, 1997;70(6):699-705. 

Weng XS. Chung Juo Chung Hsia I Chieh Ho Tsa Chih August 1995.

Yang Wei, et al. Effects of Ganoderma lucidum essence powder and Ganoderma Lucidum spore powder on immune function of mice with Lewis lung cancer. Zhong Guo Sheng Wu Zhi Pin Xue Za Zhi. 2012, (9): 1171-1175

 Yeung HC. Handbook of Chinese Herbs. Institute of Chinese Medicine, 1996.

Yoshida Y, et al. Immunomodulating activity of Chinese medicinal herbs. Intl J Immunopharmacol 1997:19(7):359. 

Yu L & Wang Y. Study on immunological activities of polysaccharides isolated from Radix codonopsis on immune function in mice. Zun Yi Yi Xue Yuan Xue Bao, 2016, (1): 10-1

 Yuan WL, Chen HZ, et al. Effect of astragalus membranaceus on electric activities of cultured rat beating heart cells infected with Coxsackie B-2 virus. Chin Med J (Engl) 1990;103(3):177-182. <2164463/a> 1371029

Zand, Janet, OMD, LAc. "Immunity: Colds & Flu." Energy Times, Sept, 1999.

Zhang Q & Shi S. Experiment research on the influence of Tu Si Zi on immune function of mice. Zhe Jiang Lin Chuang Yi Xue. 2006, (6): 568-569

Zhuang MX. The effects of polysaccharides of Astragalus membranaceus Codonopsis pilosula and Panax ginseng on some immune functions in guinea-pigs. Zhongguo yaoxue zazhi 1992;27:653-655.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.